A Case of Acute Psychosis Following Normalisation of Thyroid Status with Propylthiouracil in Long-standing Hyperthyroidism

Precipitation of acute psychosis following normalisation of thyroid status has been reported previously. Here, we report the case of a 62-year-old man with long-standing hyperthyroidism unresponsive to carbimazole, developing acute polymorphic psychotic disorder without symptoms of schizophrenia, along with normalization of thyroid status, after seven months of treatment with propylthiouracil.