Mutagenic and transforming effects of soft-X-rays with resonance energy of phosphorus K-absorption edge.
1992
Syrian golden hamster embryo (SHE) cells were exposed to synchrotron-produced monochromatic X-rays at 5·747 (2·159 keV), 5·763 (2·153 keV) and 5·779 A (2·147 keV). Although X-rays of all wavelengths induced mutations and chromatid aberrations in a dose-dependent manner, when cells were irradiated with 2·153 keV X-rays, which correspond to the resonance energy of the phosphorus K-absorption edge, the frequencies of mutation and chromatid aberration at equal dose levels were higher than for X-rays of the other wavelengths. At equal survival levels, however, there was no difference in the frequencies of mutations and chromatid aberrations in cells irradiated with soft X-rays. On the other hand, the frequency of morphological transformation in cells irradiated with 2·147 keV X-rays was higher than those irradiated with 2·153 keV and 2·159 keV X-rays. The relative biological effectiveness compared to cobalt-60 γ-rays in morphological transformation was 2·8 for 2·147 keV, 1·1 for 2·159 keV and 1·0 for 2·153 keV...
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
36
References
27
Citations
NaN
KQI