Kinetics of IgM and IgG responses in neonatally thymectomized Swiss mice under persistent immunization with sheep red blood cells.

: The kinetics of IgM and IgG responses (direct and indirect PCF) in the Swiss mice, neonatally thymectomized, injected three times a week with 5 X 10(8) sheep erythrocytes at the age of two months, were exactly the same as the controls from the same litters. The thymectomized animals showed a statistically significant decrease in both responses (18.6 and 30.2%, respectively). The kinetics of the switch from IgM to IgG and of the latter response inhibition, is the same in both the control and the thymectomized animals.