Long-term sexual functioning in germ-cell tumor survivors.

549Background: Treatment for germ-cell tumors (GCT) may lead to long-term consequences in GCT survivors. This study aimed to evaluate a long-term sexual functioning after curative treatment for GCT. Methods: GCT survivors (N = 155) from a national cancer centre completed a Sexual Function Questionnaire that was modified from PROMIS Sexual Function and Satisfaction Questionnaire at a median 10 years of follow up (range 5-32) as a primary exploratory aim. Seventeen survivors (11%) had orchiectomy alone (controls), while 138 (89%) survivors received treatment beyond orchiectomy. The study group consisted of survivors receiving a cisplatin-based chemotherapy, radiotherapy to the retroperitoneal lymph nodes or both, while the control group included survivors treated with orchiectomy only. Results: Survivors treated with both chemotherapy and radiotherapy or any treatment had difficulty maintaining erection during the intercourse compared to the controls (both P = 0.04). Moreover, patients who received chemothe...