E2F transcription factor 1 overexpression as a poor prognostic factor in patients with nasopharyngeal carcinomas

Nasopharyngeal carcinoma (NPC) is an endemic head and neck epithelial malig- nancy in Southeastern Asia and Taiwan. The E2 factor (E2F) family of transcription factors is downstream targets of the retinoblastoma protein 1. The E2F family of transcription factors