Backbone Regulation Mimicry by β‐Peptidic Foldamers: Formation of a 10‐Helix in a Mixed 6‐Strand/14‐Helix Conformational Pool

Hybrid β-peptide foldamer: Detailed NMR spectroscopy studies have revealed the formation of a new class of 10-helix in hybrid β-peptidic assembly comprised of 6-strand and 14-helical nucleating motifs. These findings show a new means of accessing intermediate secondary structures and also mimic backbone regulations in biomolecules.