Articles : A New Pyranoxanthone Inophyllin B from Calophyllum inophyllum

A new prenylated pyranoxanthone. inophyllin B (1), was isolated from the roots of Calophvlhan inophyllum (Guttiferae). Together with this compound was also isolated the known pyranoxanthone brasilixanthone B (2) and two common triterpenes friedelin (3) and sitosterol (4). Structural elucidations of these compounds were achieved through ¹H, ^(13)C, DEPT, COSY, HSQC and HMBC experiments. The molecular mass was determined using MS techniques. The crude extract indicated weak toxicity to the larvae of Aedes aegspti. We report here the isolation, structural elucidation and bioassay data for Inophyllin B and brasilixanthone B.