A Novel Method to Accurately Locate and Count Large Numbers of Steps by Photobleaching

Konstantinos Tsekouras,Thomas C. Custer,Hossein Jashnsaz,Nils G. Walter,Steve Pressé

A Novel Method to Accurately Locate and Count Large Numbers of Steps by Photobleaching

2016

Konstantinos Tsekouras
Thomas C. Custer
Hossein Jashnsaz
Nils G. Walter
Steve Pressé

A new Bayesian photobleaching trace analysis method that is computationally inexpensive can be used to treat blinking, reactivation, and overlapping events and reliably detect up to 50 fluorophores...

Keywords:

Cell biology
Bayes' theorem
Biological system
Signal-to-noise ratio
Biology
Photobleaching
trace analysis
Bayesian probability

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