Synthesis of Biaryls via Ligand-Free Suzuki-Miyaura Cross-Coupling Reactions: A Review of Homogeneous and Heterogeneous Catalytic Developments

This review describes the recent developments in the field of Suzuki-Miyaura cross-coupling reaction, in particular with regard to ligand-free catalysis. The catalysts outlined here allow convenient and green synthetic pathways specifically for the construction of C-C bonds. They enable the synthesis of biaryls by the coupling arylboronic acids with aryl halides. The literature reporting ligand-free synthesis of biaryls from 2010 to May 2015 has been reviewed.