Recurrent coronary disease in HIV‐infected patients: role of drug–drug interactions

Cardiovascular disease represents a leading comorbidity in HIV populations. Different factors may contribute to the recurrence of cardiovascular events in HIV‐infected patients. Here, we describe two patients with HIV infection and an acute coronary syndrome who developed in‐stent thrombosis after a percutaneous revascularization procedure. Also, we discuss the potential role of drug interactions between antiretroviral and antiplatelet treatments as a contributing factor for recurrent coronary disease in HIV‐infected patients.