Sa1443 Does Experience Matter? Increased ADRs in Experienced Gastroenterologists May Reflect Patient Population As Well As Technical Skill

established quality indicators for screening colonoscopy, as well as to offering sedation to the patient before the endoscopic investigation. Aim of the Study: To assess associations between the type of administered sedation and quality indices of colonoscopy. Methods: We analyzed data of 793 screening out-patients colonoscopies performed in our centre by 12 different Endoscopists between November 2013 and May 2014.Patient received intravenous analgesia with fentanyl two different regimen of moderate sedation: standard sedation with midazolam or propofol sedation administered by Gastroenterologist through Target Controlled Infusion (TCI) pump. For each patient we recorded: sex, age, ASA (American Society of Anesthesiologists) class of risk, type of sedation (standard vs propofol sedation), cecal intubation, quality of bowel preparation (low, mild, moderate or good), use of an high definition (HD) endoscope, presence or absence of polyps or cancer, number of polyps and number of detected adenomas. Multivariate logistic predictive models with panel data were generated. OR(95% CI) are reported. Results: Adenoma detection rate was predicted by age (1-yr-OR 1.05(1.03-1.06); P!0.001), propofol sedation (OR 1.70(1.06-2.71); PZ0.028) and cecal intubation (OR 3.91(1.51-10.18); PZ0.005). Cecal intubation was predicted by age (1-yr-OR 0.98(0.96-0.99); PZ0.042) and propofol sedation (OR 2.40(1.19-4.82); PZ0.014). Number of founded polyps/cancers was predicted by sex (OR 0.28(0.01-0.54); 0.038) and quality (low/mild vs moderate/good) of bowel preparation (OR -0.28(-0.46 -0.11); PZ0.001). Conclusion: In our study propofol TCI sedation does not increase PDR, but increases CIR and ADR.