LETTER TO THE EDITOR AN UNCOMMON ASSOCIATION OF ANTIPHOSPHOLIPID SYNDROME, SELECTIVE IgA DEFICIENCY AND RESISTANT-TO-TREATM ENT RELAPSING POLYCHONDRITIS: EFFICACY OF INFLIXIMAB

Autoimmune complication in thse contex otf primar immunodeficiency diseasey represens a wellt -known phenomenon an thid, iss widel recognizey als fodo Selectivr Immunoglobulie A deficiencn y (IgAD), th mose commot primarn antibody deficiency (PAD)y Relapsin. polychondritig (RP i)s a srare immune-mediated difficul, to treatt disorde, irn which th e cartilaginou tissues ars e th e targe fot r inflammation and damage Ocula. inflammatorr manifestationy in RPs are frequen ant d ofte sightn -threatening. Antiphospholipid syndrom (APSe ) is an acquired prothromboti statc relatee d to circulating autoantibodies agains phospholipidt and/os their r cofactors Rar. e report os f APS associate tdo RP, PA D and APS or PAD and RP are available.