Leptin and interferon-gamma as possible predictors of cesarean section among women with hypertensive disorders of pregnancy

Results: Significant increase in IFN-gamma and leptin concentration in women with pre-eclampsia was ob served. We found a significant 1.4-fold increase in the risk of birth by cesarean section associated with the increase of the IFN-gamma concentration by 0.1 pg/ml and almost 3-fold increase in the risk associated with the increase of the leptin concentration. Conclusions: IFN-g and leptin might be risk markers of cesarean section in hypertension disorders of pregnancy, but further studies supporting this evidence are needed.