An epidemiological survey of schizophrenia in Henan Province

Objective To investigate the morbidity rate, prevalence and influencing factors of schizophrenia among people aged 15 and above in Henan Province. Methods In 2015, a multi-stage stratified random sampling method was adopted, and the revised General Health Questionnaire (GHQ-12) was used as a preliminary screening tool to carry out mental disorder epidemiological investigation in 20 counties of Henan Province. The sampled people were divided into high, medium and low risk groups according to the GHQ-12 scores. The diagnosis of mental disorders was made by attending psychiatrist with DSM-Ⅳ-TR Axis Ⅰ diagnostic clinical interview pattern scale (SCID). The qualitative data were compared by chi-square test, and the influencing factors of schizophrenia were analyzed by Logistic regression analysis. Results A total of 23 846 people were surveyed, including 11 865 (49.76%) men and 11 981 (50.24%) women in which 124 ones were diagnosed with schizophrenia, with the adjusted lifetime prevalence rate of 5.56‰, and time point prevalence of 5.04‰. Of the 124 cases, 83 lived in towns and 41 lived in cities, 54 were male and 70 were female. The other basic message: level of education: illiterate 26, primary school 39, junior high school 47, high school or technical secondary school 9, junior or regular college 3; marital status: unmarried 31, first marriage 78, remarried 3, divorced 11, widowed 1. Univariate analysis showed statistically significant differences in the prevalence of schizophrenia at different levels of education (χ2=33.903, P<0.01) and marital status (χ2=137.143, P<0.01). Logistic regression analysis showed that urban and rural areas (Wald χ2=37.296, P<0.01), gender (Wald χ2=13.131, P<0.01), education level (Wald χ2=48.338, P<0.01), marital status (Wald χ2=54.495, P<0.01) and family history (Wald χ2=107.340, P<0.01) were the influencing factors of schizophrenia. Conclusion The prevalence rate of schizophrenia in Henan Province is basically consistent with the research results at home and abroad, and the prevention and treatment of schizophrenia should be based on different regions, ages, genders, et al. Key words: Schizophrenia; Epidemiology; Prevalence