Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): a new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomy.

Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): A new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomy Chris Parker, Matthew R. Sydes 1 , Charles Catton 2 , Howard Kynaston 3 , John Logue , Claire Murphy 1 , Rachel C. Morgan 1 , Kilian Mellon 5 , Chris Morash 6 , Wendy Parulekar 7 , Mahesh K.B. Parmar 1 , Heather Payne 8 , Colleen Savage 7 , Jim Stansfeld 9 and Noel W. Clarke 10 (The RADICALS Trial Management Group) Academic Unit of Radiotherapy & Oncology, Institute of Cancer Research and the Royal, Marsden NHS Foundation Trust, Sutton, Surrey, 1 Medical Research Council (MRC) Clinical Trials Unit, London, UK, 2 Princess Margaret Hospital, Toronto, Ontario, Canada, 3 Department of Urology, University Hospital of Wales, Heath Park, Cardiff, 4 Christie Hospital NHS Trust, Manchester, UK, 5 Urology Section, University of Leicester, UK, 6 University of Ottawa, The Ottawa Hospital General Campus, Ottawa, 7 National Cancer Institute of Canada (NCIC) Clinical Trials Group, Kingston, Ontario, Canada, 8 Department of Oncology, University College Hospital, London, UK, 9 Hon. Treasurer, PCaSO Prostate Cancer Network, Emsworth, Hants, UK, 10 Salford Royal Hospitals NHS Trust, Salford, UK