3-methyl-4-methyl-cytidine and uridine nucleoside compounds, its synthesis and pharmaceutical use

The present invention discloses a 4-methyl-3-methyl-uridine and cytidine nucleoside compounds, its synthesis and pharmaceutical use, is the field of medicinal chemistry. Such compounds have the general structure:, these compounds and a base of the sugar ring is modified at the same time, increase the activity and reduce the toxicity of the compound, provides a better prospect for the development of such compounds, can be applied preparation of anti-HBV drugs. Synthesis method is simple, provides the conditions for the synthesis of a large number of such compounds.