sensitivity and RNA viral load using genetically diverse virus isolates

a b s t r a c t Background: HIV antigen/antibody (Ag/Ab) combination assays represent a significant advancement in assays used for diagnosing HIV infection based on their ability to detect acute and chronic infections. During acute HIV infection (AHI), detection depends on assay sensitivity for p24 Ag. Objective: To directly compare the Ag sensitivity of the ARCHITECT