Nasal Obstruction in Children With Cleft Lip and Palate: Results of a Cross-Sectional Study Utilizing the NOSE Scale:

Objective:To characterize the epidemiology and risk factors for nasal obstruction among subjects with cleft lip and/or cleft palate (CL/P) utilizing the well-validated Nasal Obstruction Symptom Evaluation (NOSE) survey.Design:Retrospective cross-sectional study.Setting:Cleft Lip and Palate Program, Children’s Hospital of Philadelphia.Patients, Subjects:One thousand twenty-eight surveys obtained from 456 subjects (mean age: 10.10 (4.48) years) with CL/P evaluated between January 2015 and August 2017 with at least 1 completed NOSE survey.Interventions:Nasal Obstruction Symptom Evaluation surveys completed at each annual visit.Main Outcome Measures:Composite NOSE and individual symptom scores.Results:Sixty-seven percent of subjects had nasal obstruction at some point during the study period, with 49% reporting nasal obstruction at latest follow-up. subjects aged 14 years and older reported the most severe symptoms (P = .002). Subjects with cleft lip and alveolus (CL+A) and unilateral cleft lip and palate (CL...