A long term clinical observation in patients with obstructive sleep apnea/hypopnea syndrome treated by autocontinuous positive airway pressure

Objective To observe the changement of body mass index (BMI),apnea hypopnea index (AHI),lowest pulse oxygen saturation (LSPO2),micro-arousal index (MAI),percentage of sleep Ⅰ ～ Ⅱ stage time and Ⅲ ～ Ⅳ stage time in the total time ( Ⅰ ～ Ⅱ％,Ⅲ ～ Ⅳ ％) in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) who had been treated with auto-continuous positive airway pressure (AUTO-CPAP) for two years.Methods The 42 patients who were diagnosized OSAHS with polysomnography (PSG) had been treated with AUTO-CPAP for two years,and the treatment time was not less than 5 hours pre day.The second PSG was taken in this patients after a two-years treatment.To observe the changement of the BMI,AHI,LSPO2,MAI,Ⅰ ～ Ⅱ ％,Ⅲ ～ Ⅳ ％ from pre-treatment to post-treatment.Results The BMI showed no difference between pre-treatment and post-treatment ( P ＞0.05).When the treatment being quitted,AHI reduced (6.8±3.2) times/h from (43.6±12.6) times/h to (36.7±11.2) times/h (P ＜0.05).And LSPO2 raised (7.1±2.6)％ from (69.3±10.2)％ to (76.4±8.1)％ (P ＜0.05).The MAI raised (2.1±3.2) times/h from (38.1±12.2) times/h to (44.2± 13.1) times/h ( P ＜0.05).And Ⅰ ～ Ⅱ ％,Ⅲ ～ Ⅳ ％ shows no difference between pre treatment and post-treatment ( P ＞0.05).Conclusions A long term treatment with AUTO-CPAP shows likely no influence to the BMI of the patients with OSHAS.A long term treatment with AUTO-CPAP is maybe benefit to the AHI and LSPO2.When the treatment being quitted,the influence to the patient not lies in Ⅰ ～ Ⅱ ％ or Ⅲ ～Ⅳ ％ but in the MAI. Key words: Obstructive sleep apnea-hypopnea syndrome;  Auto-continuous positive airway pressure;  Body mass index;  Apnea hypopnea index;  Micro arousal index