Ornidazole purity rubric material and preparation method and application

The invention discloses Ornidazole purity rubric material and preparation method and application.Its preparation method, comprises the following steps：1) Ornidazole material powder is sampled, its content is determined using high performance liquid chromatography area normalization method, obtains the purity definite value of Ornidazole material powder；2) weight/mass percentage composition of Ornidazole material powder reclaimed water, non-volatile impurities and organic volatile impurities is determined, is calculated according to formula I, is obtained the purity definite value 1 of Ornidazole purity rubric material, be designated as P HPLC‑AN ；P HPLC‑AN =P 0 × [100% X w ‑X n ‑X v ] formula I；3) take Ornidazole material powder to determine its content using quantitative nuclear-magnetism method, obtain the purity definite value 2 of Ornidazole purity rubric material, be designated as P NMR ；4) P is calculated HPLC‑AN And P NMR Average value, that is, obtain the purity definite value of Ornidazole purity rubric material.The present invention can be used for the detection of animal products drug residue as standard substance, and technical support and material guarantee are provided for national agricultural product quality and safety risk assessment and the foundation of monitoring traceability system.