Clinical efficacy of peppermint oil capsules combined with Domperidone in the treatment of bile reflux gastritis after gastric surgery

Objective To observe the clinical efficacy of peppermint oil capsules combined with domperidone in the treatment of bile reflux gastritis(BRG) after gastric surgery. Methods Totally 47 patients with BRG after gastric surgery were treated with peppermint oil capsule(0.9g,tid)and domperidone(10mg,tid). Each patient's gastroscopic manifestations and histopathology were rechecked after 4 weeks. The efficacy was observed on the improvement of symptoms and gastric mucosal injury, and on the reduction of bile reflux. Results 42 patients attained satisfactory therapeutic effect with the total efficiency rate of 89.4%.No adverse effects during the treatment period. Conclusion Peppermint oil capsules combined with domperidone shows better efficacy in treatment of BRG after gastric surgery. Key words: Peppermint oil; Gastritis; Bile reflux