Image-Based Subthalamic Nucleus Segmentation for Deep Brain Surgery with Electrophysiology Aided Refinement

Identification of subcortical structures is an essential step in surgical planning for interventions such as the deep brain stimulation (DBS), in which permanent electrode is implanted in a precisely defined location. For refinement of the target localisation and compensation of brain shift occurring during the surgery, intra-operative electrophysiological recording using microelectrodes is usually undertaken.