Abstract 19897: Preclinical Evaluation of Proangiogenic Gene Therapy by Ultrasound Targeted Microbubble Destruction of Vascular Endothelial Growth Factor Minicircle DNA in a Model of Severe Peripheral Arterial Disease in Watanabe Heritable Hyperlipidemic Rabbits

Hao H. Chen,Michael A. Kuliszeski,D. Rudenko,Howard Leong-Poi

Abstract 19897: Preclinical Evaluation of Proangiogenic Gene Therapy by Ultrasound Targeted Microbubble Destruction of Vascular Endothelial Growth Factor Minicircle DNA in a Model of Severe Peripheral Arterial Disease in Watanabe Heritable Hyperlipidemic Rabbits

2017

Hao H. Chen
Michael A. Kuliszeski
D. Rudenko
Howard Leong-Poi

Background: Ultrasound targeted microbubble destruction (UTMD) is a non-invasive technique for gene delivery. We have previously shown that UTMD of vascular endothelial growth factor (VEGF) plasmid...

Keywords:

Vascular endothelial growth factor
Genetic enhancement
Plasmid
Peripheral artery disease (PAD)
Angiogenesis
Cancer research
Cardiology
Internal medicine
Gene delivery
Diabetes mellitus
Minicircle
Medicine
Peripheral

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