Highly Sensitive Electrochemical Sensor for the Detection of Anions in Water Based on a Redox-Active Monolayer Incorporating an Anion Receptor

In the present work, gold electrodes were modified using a redox-active layer based on dipyrromethene complexes with Cu(II) or Co(II) and a dipodal anion receptor functionalized with dipyrromethene. These modified gold electrodes were then applied for the electrochemical detection of anions (Cl–, SO42–, and Br–) in a highly diluted water solution (in the picomolar range). The results showed that both systems, incorporating Cu(II) as well as Co(II) redox centers, exhibited highest sensitivity toward Cl–. The selectivity sequence found for both systems was Cl– > SO42– > Br–. The high selectivity of Cl– anions can be attributed to the higher binding constant of Cl– with the anion receptor and the stronger electronic effect between the central metal and anion in the complex. The detection limit for the determination of Cl– was found at the 1.0 pM level for both sensing systems. The electrodes based on Co(II) redox centers displayed better selectivity toward Cl– anion detection than those based on Cu(II) cente...