Acid-catalyzed synthesis of functionalized arylthio cyclopropane carbaldehydes and ketones
2018
A general strategy for the synthesis of arylthio cyclopropyl carbaldehydes and ketones via a Bronsted acid catalyzed arylthiol addition/ring contraction reaction sequence has been exploited. The procedure led to a wide panel of cyclopropyl carbaldehydes in generally high yields and with broad substrate scope. Mechanistic aspects and synthetic applications of this procedure were investigated.
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