Cerebral Infarction in Patients Aged 15 to 40 Years

Background and Purpose Cerebral infarction among young adults has been little studied in Brazil. Most studies adopt a variable upper age limit and often use the term “young” to designate different age ranges. The objective of the present study was to determine possible differences in etiology of cerebral infarction in specific age subpopulations. Methods We studied 106 patients aged 15 to 40 years and divided them into two subpopulations by age at time of ictus (ie, 15 to 29 years and 30 to 40 years). On the basis of Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria, we classified the patients into the following five groups: (1) large-artery atherosclerosis, (2) small-vessel occlusion or lacunae, (3) cardioembolism, (4) other determined causes, and (5) undetermined causes. The proportions for each group were compared between the two age ranges to determine whether there was a significant difference in group distribution. Results The proportions were different between the two age ranges, with a...