HYPERCONTRACTILITY IN WOMEN WITH HIGH RESTING CORONARY VELOCITY AND LOW CORONARY FLOW RESERVE: RESULTS FROM THE WOMEN'S ISCHEMIA SYNDROME EVALUATION-CORONARY VASCULAR DYSFUNCTION (WISE-CVD) PROJECT

Women with evidence of ischemia and non-obstructive coronary artery disease (INOCA) often have impaired coronary flow reserve (CFR). Importantly, in patients with low CFR high resting coronary blood flow velocity is associated with worse prognosis, including heart failure development, although