Impact of Acute Normovolemic Hemodilution in Organ and Cell Structure

Rigorous control procedures adopted presently by blood banks have reduced transfusionassociated risks, such as transmission of infectious diseases. Nevertheless, other complications related with blood-transfusions remain, such as transfusion-related acute lung injury (TRALI) and other immune disorders. In critically ill patients, transfusion has been associated with increase in morbidity and mortality, so that restrictive transfusion strategies have been proposed, which have reduced incidence of organ dysfunction as well as of other complications (Hajjar et al., 2010; Hebert et al., 1999).