[Effect of two short striae incision or traditional "L" shaped incision in neck dissection of differentiated thyroid carcinoma on serum trauma cytokines].

Objective: To compare the trauma of neck dissection on the human body between two-striae incision and traditional "L" shaped incision by serum trauma cytokines.Methods: Patients with differentiated thyroid carcinoma hospitized from December 2008 to July 2011 were divided into 2 groups according to their own will.The first group 26 patients) had two-striae incision and the second group 32 patients) had traditional "L" shaped incision.The serum level of interleukin(IL)-2,IL-6 and C-reactive protein(CRP) in all patients were examined 1 day before and 1,3 and 5 days after the surgery.Results: No statistical significance was found between the 2 groups,although level of IL-2 decreased 1 day after the surgery,but recovered to normal 3 days later.The level of IL-6 in both groups increased 1 day after the surgery,began to decrease 3 days after the surgery,and recovered to normal 5 days after the surgery.The level of CRP suggested statistical significance(P0.05),which increased obviously 1,3 and 5 days after the surgery.No statistical difference was found before or after the surgery between the 2 groups(P0.05).After follow-up for 8–40 months,no local recurrence or lymph node metastasis was found.Conclusion: Compared with the traditional "L" shaped incision,two-striae incision in neck dissection does not increase the serum level of trauma cytokines and trauma to human body after the surgery.Two-striae incision is an ideal surgical approach to differentiated thyroid carcinoma.