Structural changes in the intraorgan hepatic arteries during experimental aortic coarctation

: Structural changes of intraorganic hepatic arteries were studied in 8 control dogs and 20 pups with hemodynamic model of aorta coarctation. Experimental animals were observed within the terms from 1 month to one year. Histological and morphological methods were used to assess the state of hepatic vessels. The investigations performed resulted in the discovery of the complex of adaptive and pathological changes in the hepatic arterial bed. The first were the reactive atrophy of the hepatic arteries wall with decrease of smooth myocytes number and parameters in the media and the appearance of musculo-elastic sphincters, Conti pillows and smooth myocytes bundles in the intima. The latter lied in the arterial and arteriolar wall sclerosis in liver. Pathological changes grow proportionally with the terms of the experiment.