Influence of Temperature and Relative Humidity on Human Rotavirus Infection in Japan

A climatologic analysis of human rotavirus infection in inpatients with acute diarrhea was conducted over a seven-year period. The infection frequency appeared to be related to temperature, but not to relative humidity. Human rotavirus infection was found to appear abruptly when the mean temperature of any 10-day period became 20 C (June and July) in the city of Yamagata in northern Japan. The use of electron microscopy for the detection of viruses in the feces of diarrheal children led to