Optrode for Multimodal Deep-brain Infrared Stimulation☆

Abstract In recent years, optical stimulation in neuroscience has emerged as an alternative to electrical stimulation. In this work, we present the concept and optical simulation of an optrode capable of delivering focused infrared light to brain tissue, while simultaneously recording electrical signals from the surrounding area. The system combines the advantages of silicon microfabrication and silicon's transparency in the near-infrared. For efficient coupling into the probe and controlling the illuminated volume in the brain, silicon microlenses were simulated using MATLAB. The lens system can focus light in 2-D, with configurable focal length and spot size.