A convergent synthesis of the renin inhibitor CGP60536B

David Andrew Sandham,Roger John Taylor,John S Carey,Alexander Dr. Fässler

A convergent synthesis of the renin inhibitor CGP60536B

2000

David Andrew Sandham
Roger John Taylor
John S Carey
Alexander Dr. Fässler

Abstract Pseudoephedrine serves as a dual purpose chiral auxiliary and protecting group in the synthesis of the novel orally active renin inhibitor CGP60536B.

Keywords:

Alkylation
Combinatorial chemistry
Enantioselective synthesis
Pseudoephedrine
Convergent synthesis
Stereochemistry
Renin inhibitor
Chemistry
Protecting group
Chiral auxiliary
Active Renin
Organic chemistry

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