HPPD variants and usage procedures

An isolated nucleic acid comprising a nucleotide sequence encoding a mutated HPPD protein, wherein said mutated HPPD protein has HPPD activity and wherein in said mutated HPPD protein the amino acid at a position corresponding to position 280 of the SEQ ID NO: 2 has been replaced such that the resulting amino acid sequence comprises amino acid Ala at the position corresponding to position 280 of the amino acid sequence of SEQ ID NO: 2: