SYNTHESES AND CHARACTERISATION OF MOLECULAR TWEESORS FOR THE RECOGNITION OF GUEST SUBSTRATES

Two novel amido anion receptors were synthesized from building block 3,3’ methylene diamine and was characterized via the techniques of 1 H NMR, 13 C NMR, DEPT- 135 spectroscopy, 1 H- 1 H COSY, HMQC and HMBC. Preliminary anion binding studies via 1 HNMR spectroscopy revealed complexation with phosphate anions in the highly competitive solvent, d 6-DMSO. This paper focuses on the syntheses, characterization and preliminary anion binding studies of molecular clef type receptors (4) and (5) incorporating the amide, -HNCOunits. These receptors are built on the molecular scaffold of 3,3’ methylene diamine and present convergent binding sites to anionic substrates.