Histolgical and immunohistochemical study of malignant myoepithelioma of salivary glands

: Histological and immunohistochemical features of 12 cases of malignant myoepithelioma of the salivary glands were studied.There were 4 major histologic types in the tumor tissues:(1)clear tumor cells proliferated mainly with or without keratin peral;(2)spindle shaped tumor cells proliferated mainly with or without mucoid regions;(3)plasmacytoid(hyaline) tumor cells were arranged in adenoid configurations.In the immunohistochemical studies,the tumor cells were positive for actin;myosin;glial,fibrillary,acidic,protein.(GFAP);S-100 protein antibodies.The authors consider that the application of the above-mentioned antibodies may assist in the differentiated diagnosis of malignant myoepithlioma.