Interleukin 6, interleukin 1 β, estradiol and testosterone concentrations in serum and follicular fluid of females with stimulated and non-stimulated ovaries

β were measured. The results show that serum concentration of testosterone was significantly higher in non stimulated cases. Also, the serum and follicular fluid concentrations of interleukin 6 and interleukin 1 β β β β in stimulated cases were significantly higher than non stimulated group. There was an important negative correlation between the level of testosterone in patient's serum and IL-6 and IL-1β levels of follicular fluid. In conclusion, according to these results, it seems that the levels of testosterone and IL-6 and IL-1β in patient's serum and follicular fluid are a good factor for prediction of maturity of oocytes.