Morphometric analysis of subchondral bone of the tibial condyle in osteoarthrosis

Tibial condyles in 11 patients with knee joint osteoarthrosis were analyzed by subchondral bone morphometry using 11 static parameters. The results were evaluated by comparison with the grade of joint cartilage degeneration in relation to the external, intermediate, and internal areas of the tibial condyle. The bone morphometric data also were analyzed according to the depth of layers, from the surface to the depth of 2000 μm of the bone. A parallel relationship between the bone volume/bone formation activity and the Mankin grade of cartilage degeneration was noted in both medial and lateral condyles. Bone resorption activity in the medial condyle was found only in the external and intermediate areas; it was extremely low in the lateral condyle