Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis.

Hua Zhang,Yongyuan Ma,Xinying Cheng,Dong-Bo Wu,Xingming Huang,Bin Chen,Yafeng Ren,Wei Jiang,Xiaoqiang Tang,Ting Bai,Yutian Chen,Yilin Zhao,Chunxue Zhang,Xia Xiao,Jing Liu,Yue Deng,Tinghong Ye,Lu Chen,Han-min Liu,Scott L. Friedman,Liping Chen,Bi-Sen Ding,Zhongwei Cao

Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis.

2021

Chronic hepatic diseases such as nonalcoholic steatohepatitis (NASH) suppress liver regeneration and lead to fibrosis and cirrhosis. Decoding the cellular and molecular network underlying this fibr...

Keywords:

vascular niche
nonalcoholic steatohepatitis
liver fibrosis
Cirrhosis
Liver regeneration
Pathology
molecular network
Medicine
Chronic hepatic
Fibrosis

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