CANNABIS, HYPOCHLORHYDRIA, AND CHOLERA

Abstract In 90 volunteers participating in a vaccine-development programme consumption of beer more than 3 days a week was linked with high stomach acid output, and smoking of cannabis >2 days a week was linked with low acid output. In 92 volunteers challenged with Vibrio cholerœ or enterotoxigenic Escherichia coli, heavy use of cannabis was associated with more voluminous diarrhœa. Cannabis use may be an important factor predisposing to severe diarrhœa.