Human exposure modelling of quercetin in onions (Allium cepa L.) following thermal processing

Abstract Post-harvest treatment can influence levels of secondary metabolites in fruits and vegetables. Onions contain high levels of quercetin but are commonly heat-treated before consumption. Hence, the objective of this study was to examine the effect of cooking treatments on the flavonoid (3,4′-Qdg and 4′-Qmg) concentrations in onion and to determine, by simulation modelling, probable human exposure. Onion samples ( n  = 3) were cooked using three processes (fry, bake and steam) for three time intervals (5, 10 and 15 min). Frying ( 50%. Thermal processing (>10 min) was shown to decrease quercetin content in all samples. The simulation model predicted human absorption and exposure. Steaming (15 min) resulted in the lowest quercetin exposure, with mean values of 4000 and 400 μg/day for 3,4′-Qdg and 4′-Qmg, respectively. Untreated onions had mean exposures of 14,000 and 3000 μg/day for 3,4′-Qdg and 4′-Qmg, respectively.