To study the hematological parameters in covid-19 positive cases in different clinical categories

2020 
Aims & Objectives: Since it's origin in December 2019 Novel Corona virus infection has behaved in an unprecedented manner A number of studies had been done so far to find out peculiar characteristics about this disease However, few studies have shown varied hematological manifestations of this which have been found to have prognostic implications In this study we aim to assess the hematological parameters of COVID-19 positive cases and in their different clinical categories (mild, moderate and severe) Patients/Materials & Methods: It is an observational study done in Himalayan Institute of medical sciences, Dehradun (1) Number of cases included were 118 over 3 months duration (July, August, September-2020) (2) The relevant clinical details of all the COVID-19 positive patients such as name, age, UHID were recorded (3) EDTA sample was run on DXH800 (Beckmencoulter automated analyzer) and all parameters were recorded including the VCS Inclusion criterion: Patients diagnosed with COVID-19 on Rapid antigentestor RTPCR of all age groups Exclusioncriterion:Patients with missing hematological parameters Results: In our study, total number of cases included were 118, out of which 84 (71 18%) were males and 34 (28 81%) were females Patients above 60 years were 35 (29 6%) The patients were categorized into mild, moderate and severe on the basis of clinical findings and those findings were co-related with the VCS parameters The significant findings include decreased absolutely mphocytecount in 43 2% cases and absolute eosinopenia in 83 05% of cases, absolute neutrophil count was increased in 44 9% cases and platelet count was reduced in 30 5% of the cases Discussion & Conclusion: In major number of cases absolute lymphocyte count, absolute eosinophil count and neutrophil to lymphocyte ratio was found significant;so it is advised to categorize patients on the basis of clinical findings and related VCS parameters for early COVID-19 testing
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