길경이 고지방식이로 유발된 비만흰쥐의 체중 및 혈청중지질성분의 변화에 미치는 영향

Objectives : This experimental study was designed to investigate the effects of Platycodon grandiflorum powder on body weight and serum biological composition. Methods : A series of experiments have been conducted in order to measure the effects of the body weight changes and serum lipid profiles. The measurement have been performed on; (1) the changes amount of body weight; (2) the quantity of total cholesterol, triglyceride, free fatty acid in serum. Results : Rats given feed containing high fat and Platycodon grandiflorum powder showed significant decrease in net weight gain in comparison with high fat diet feeding group. The quantity of total cholesterol, triglyceride, free fatty acid in serum was significant decrease in high fat and Platycodon grandiflorum powder group in comparison with that of high fat feeding group. Conclusion : Results of our research in this paper show that Platycodon frandiflorum powder might improve lipid composition and body wight in rats Fed with high fat diet.