Mesenchymal stem cells therapy in acute renal failure: Possible role of hepatocyte growth factor

Management of acute renal failure depends first on correction of the metabolic abnormalities like the correction of hyperkalemia and correction of metabolic acidosis then treatment of the cause as correction of the hypovolemic state during shock or immunosuppressive therapy for glomerulonephritis [3]. Although a number of agents and growth factors have been proven effective in the amelioration of ARF in otherwise healthy animals, no significantly effective new therapy has been introduced into clinical practice in decades. It is for these reasons that fundamentally new strategies for the treatment of ARF are needed.