Abstract P732: Genetic Ablation of Endothelial C3a-Receptor Confers Cerebrovascular Protection Independent of the Dynamics of Reperfusion in Stroke

Adam Kindelin,Sara Bowen,Saif Ahmad,Michael F. Waters,Nasrul Hoda,Andrew F. Ducruet

Abstract P732: Genetic Ablation of Endothelial C3a-Receptor Confers Cerebrovascular Protection Independent of the Dynamics of Reperfusion in Stroke

2021

Adam Kindelin
Sara Bowen
Saif Ahmad
Michael F. Waters
Nasrul Hoda
Andrew F. Ducruet

Background: Stroke enhances endothelial C3a Receptor (C3aREnd) expression and humoral levels of C3a which is further exacerbated by intravenous thrombolysis (IVT). Therefore, it is critical to inve...

Keywords:

Thrombolysis
Internal medicine
Cardiology
Thrombosis
genetic ablation
Stroke
Medicine
Blood–brain barrier
C3a receptor

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