Epidemiological and clinical features of 24 rabies

Objective To understand epidemiological and clinical features of rabies to improve diagnosis and treatment level and enhance capacity in rabies prevention and control.Methods 24 cases of human raties recruited in Beijing Ditan hospital during November,2008 to December,2010 were investigated.Results Major cases were young and middle-aged,male,living in rural area,disease occurred mainly in summer,incubation period,which was consistent with rules,increased with the distance between exposure site and head.36.8％ went through post exposure treatment,15.8％ received post-exposure vaccination,only 5.3％ were injected with received rabiesimmune globulin or serum,onset symptoms of 25％ cases were hydrophobia,fear of wind,almost all cases presented with typical symptoms such as hydrophobia,fear of wind,salivation; 70.8％ appeared more than one complications,average natural disease course was 5.92 ±3.8 days,41.7％ were misdiagnosed during first clinical visit,but there were no difference of accurate diagnosis rate in second and third level hospitals.Conclusion because rabies has 100％case fatality rate,causing great harm to public health,it holds great importance to prompt application of pathogenic diagnosis into clinical diagnosis and implement active prevention and control measures. Key words: Rabies;  Epidemiology;  Clinic features