2440-PUB: Characterization of Cardiometabolic Risk Profiles of Individuals Presenting to an Urban Medical Center in Cambodia with Prediabetes and T2DM

Introduction: The prevalence of prediabetes and T2DM is increasing globally, and especially in developing countries like Cambodia. Comparisons between metabolic risk profiles of patients with prediabetes and T2DM in Cambodia have not previously been reported. Aims: To compare the clinical characteristics of patients with newly diagnosed prediabetes and T2DM who presented to the Community Medical Center in Phnom Penh, Cambodia. A secondary aim was to determine if any sex differences exist among individuals with T2DM. Methods: A retrospective study of 763 patients diagnosed with prediabetes or T2DM from July 2015 to July 2018 who had a complete biophysical profile. Comparisons were performed between groups using unpaired Student’s t-test. Results: Results are summarized in Table 1. Individuals with prediabetes had lower TG levels but otherwise had similar cardiometabolic risk profiles to those with T2DM. Females compared to males with T2DM presented with lower HbA1c levels, but with higher corrected waist circumferences, higher LDL, and a greater number of cardiometabolic risk factors. Conclusion: Cardiometabolic risk profiles were nearly indistinguishable in those with newly diagnosed prediabetes and T2DM. While females with T2DM presented with lower HbA1c values, they had a greater number of cardiometabolic risk factors compared to males. Disclosure A. Haas: None. S. Peng: None. P. Menh: None. P.G. Curran: None. M. Hudson: None. Funding National Institutes of Health