Complex evaluation of neuropsychological cognitive and emotional personality disorders in multiple sclerosis

UNLABELLED: 30 patients with definite MS and mild or moderate disability were tested with expended neuropsychological, psychiatric, psychological, neurological, neurophysiological, MRI methods. The aim of the study was to analyse the role of cognitive, emotional and personal peculiarities in MS clinical picture and its influence on patients adaptation and quality of life. It was found, that patients with MS had high level of personal anxiety, emotional ways of coping and low scores in constructive reasoning, narrowing of motivation sphere. Neuropsychological test performance revealed low level in activation, regulatory and operation brain processing connected with dysfunction in relations of profound structures with frontal brain and dysfunction of temporal-occipital zones of right hemisphere and also with connections between hemispheres. CONCLUSION: All changes had relationship with brain MRI abnormalities and neurophysiological characteristics.