Application of sevoflurane inhalation anesthesia in children

Objective To observe the clinical effects of sevoflurane inhalation anesthesia in children. Methods Forty children aged 3-10 years old were divided randomly into two group S with 20 cases each.Sevoflurane was inhaled(8% sevoflurane in 4 L/min oxygen for anesthesia induction and 2%～3% sevoflurane for the maintenance) in group S.Ketamine was injected intravenously (2 mg/kg for the induction and 20～50 μg·kg-1·min-1 for the maintenance) in group K. Fentanyl 2 μg/kg and atracurium 0.5 mg/kg were injected after loss of eyelash reflex. The MAP,HR,SpO2% and incidences of excitatory activity movement,nausea and vomiting during recovery were recorded.ResultsAnesthesia induction of both groups was smooth.Compared with group K,MAP and HR were significantly lower after injected ketamine in group S(P0.05).The awake time of group S was shorter than that of group K [(8.2±2.4) min vs.(13.7±3.2) min] (P0.01).The incidences of adverse reaction during recovery in group S was lower than that in group K.Conclusion Compared to ketamine anesthesia,sevoflurane inhaiation has the advantages of rapid induction and recovery,less side effects during recovery.