Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance

Carolina Peña-Martínez,Violeta Durán-Laforet,Alicia García-Culebras,Fernando Ostos,Macarena Hernández-Jiménez,Isabel Bravo-Ferrer,Alberto Pérez-Ruiz,Federico Ballenilla,Jaime Díaz Guzmán,Jesús M. Pradillo,Ignacio Lizasoain,María A. Moro

Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance

2019

Carolina Peña-Martínez
Violeta Durán-Laforet
Alicia García-Culebras
Fernando Ostos
Macarena Hernández-Jiménez
Isabel Bravo-Ferrer
Alberto Pérez-Ruiz
Federico Ballenilla
Jaime Díaz Guzmán
Jesús M. Pradillo
Ignacio Lizasoain
María A. Moro

Background and Purpose— Recanalization of the occluded artery is a primary goal in stroke treatment. Unfortunately, endovascular treatment is not always available, and tPA (tissue-type plasminogen ...

Keywords:

Physical therapy
Diabetes mellitus
Pharmacology
Plasminogen activator
Neutrophil extracellular traps
THROMBOTIC STROKE
Medicine
pharmacological modulation
Inflammation
Platelet
tissue type
Artery

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